The effect of therapy of the lower urinary tract symptoms due to prostatic benign enlargement on erectile function

Background: Benign prostatic enlargement is the most common benign disease in men. The main cause for the emergence of benign prostatic enlargement is sexual hormone testosterone. Under the influence of enzyme 5-alpha reductase testosterone turns into active dihydrotestosterone, which is then combin...

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Permalink: http://skupnikatalog.nsk.hr/Record/nsk.NSK01001108060/Details
Matična publikacija: Journal of applied health sciences (Online)
6 (2020), 1 ; str. 77-82
Glavni autori: Štraus, Anja (Author), Poteko, Sandi, Starc, Andrej
Vrsta građe: e-članak
Jezik: eng
Predmet:
Online pristup: https://doi.org/10.24141/1/6/1/8
Journal of applied health sciences (Online)
Hrčak
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024 7 |2 doi  |a 10.24141/1/6/1/8 
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041 0 |a eng  |b eng  |b hrv 
042 |a croatica 
044 |a ci  |c hr 
080 1 |a 616  |2 2011 
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100 1 |a Štraus, Anja  |4 aut  |9 HR-ZaNSK 
245 1 4 |a The effect of therapy of the lower urinary tract symptoms due to prostatic benign enlargement on erectile function  |h [Elektronička građa] /  |c Anja Štraus, Sandi Poteko, Andrej Starc. 
300 |b Graf. prikaz. 
504 |a Bibliografske bilješke na kraju teksta. 
504 |a Summary ; Sažetak. 
520 |a Background: Benign prostatic enlargement is the most common benign disease in men. The main cause for the emergence of benign prostatic enlargement is sexual hormone testosterone. Under the influence of enzyme 5-alpha reductase testosterone turns into active dihydrotestosterone, which is then combined with receptors and causes the growth of the prostate. Benign prostatic enlargement can cause the lower urinary tract symptoms. One of the treatment options of lower urinary tract symptoms due to benign prostatic enlargement is the treatment with medicaments – inhibitors 5-alpha reductase. Like any other medicament, this one can also have unpleasant side effects, between others reduced erectile function and reduced libido. Methods: We used the International Index of Erectile Function (IIEF-5), Quality of Erection Questionnaire (QEQ), and demographic data. Results: Men with benign prostatic enlargement have problems with keeping an erection even before starting the therapy with medicaments. After the therapy with inhibitors 5-alpha reductase the results of the research show that on the erectile function scale, there are no significant differences between the first and second measurement, but on the erectile dysfunction scale expected differences occur – the functionality decreases. We also noticed that the independent variables of age and employment status have influence on the result of medicament treatment in the way that older participants in the study have more issues with erectile function than younger ones. Secondly, the men in retirement have more problem than employed men. There were no noticeable connections between the level of completed education and the profession of the participants. Conclusions: The results of the research were expected, according to the previously consulted literature, where the side effects of treatment with medicaments inhibitors 5-alpha reductase were already mentioned. The effects that the treatment has on erectile functio 
520 |a Uvod: Dobroćudno povećanje prostate je najčešća dobroćudna bolest u muškaraca. Glavni uzročnik pojave dobroćudnog povećanja prostate je muški spolni hormon testosteron. Pod utjecajem enzima 5-alfa reduktaze testosteron se pretvara u aktivni dihidrotestosteron, koji se tada kombinira s receptorima i uzrokuje rast prostate. Dobroćudno povećanje prostate može uzrokovati simptome u donjem mokraćnom sustavu. Jedna od mogućnosti liječenja simptoma donjeg dijela mokraćnog sustava uslijed dobroćudnog povećanja prostate je liječenje lijekovima - inhibitorima 5-alfa reduktaze. Kao i bilo koji drugi lijek, i ovaj može imati neugodne nuspojave, između ostalih smanjenu erektilnu funkciju i smanjeni libido. Metode: Koristili smo međunarodni indeks erektilne funkcije (IIEF-5), upitnik o kvaliteti erekcije (QEQ) i demografske podatke. Rezultati: Muškarci s benignim povećanjem prostate imaju problema s održavanjem erekcije, čak i prije nego što započnu terapiju lijekovima. Nakon terapije inhibitorom 5-alfa reduktaze rezultati istraživanja pokazuju da na ljestvici erektilne funkcije nema značajnih razlika između prvog i drugog mjerenja, ali na ljestvici erektilne disfunkcije dolazi do očekivanih razlika - funkcionalnost opada. Također smo primijetili da nezavisne varijable dobi i zaposlenja imaju utjecaj na rezultat liječenja lijekovima na način da stariji sudionici u istraživanju imaju više problema s erektilnom funkcijom od mlađih muškaraca. Zatim, muškarci u mirovini imaju više problema nego muškarci koji su zaposleni. Nisu bile uočljive veze između završene razine obrazovanja i profesije sudionika. Zaključci: Rezultati istraživanja bili su očekivani, prema prethodno konzultiranoj literaturi, gdje su već spomenute nuspojave liječenja inhibitorima 5-alfa reduktaze. Učinak koji tretman ima na erektilnu funkciju je pogoršanje funkcije, zato je važno potražiti pomoć liječnika odmah nakon što se pojavi. 
653 0 |a Prostata  |a Dobroćudne bolesti  |a Erektilna funkcija  |a Farmakoterapija  |a Mokraćni sustav 
700 1 |a Poteko, Sandi  |4 aut  |9 HR-ZaNSK 
700 1 |a Starc, Andrej  |4 aut 
773 0 |t Journal of applied health sciences (Online)  |x 2459-5640  |g 6 (2020), 1 ; str. 77-82  |w nsk.(HR-ZaNSK)000935492 
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