Integrated diagnostics

The current scenario of in vitro and in vivo diagnostics can be summarized using the "silo metaphor", where laboratory medicine, pathology and radiology are three conceptually separated diagnostic disciplines, which will increasingly share many comparable features. The substantial progress...

Full description

Permalink: http://skupnikatalog.nsk.hr/Record/nsk.NSK01001102502/Details
Matična publikacija: Biochemia medica (Online)
30 (2020), 1 ; str. 18-30
Glavni autori: Lippi, Giuseppe (Author), Plebani, Mario
Vrsta građe: e-članak
Jezik: eng
Predmet:
Online pristup: https://doi.org/10.11613/BM.2020.010501
Biochemia medica (Online)
Hrčak
LEADER 02980naa a22003734i 4500
001 NSK01001102502
003 HR-ZaNSK
005 20210716101127.0
006 m d
007 cr||||||||||||
008 210527s2020 ci d |o |0|| ||eng
024 7 |2 doi  |a 10.11613/BM.2020.010501 
035 |a (HR-ZaNSK)001102502 
040 |a HR-ZaNSK  |b hrv  |c HR-ZaNSK  |e ppiak 
041 0 |a eng  |b eng 
042 |a croatica 
044 |a ci  |c hr 
080 1 |a 61  |2 2011 
080 1 |a 577  |2 2011 
100 1 |a Lippi, Giuseppe  |4 aut 
245 1 0 |a Integrated diagnostics  |h [Elektronička građa] :  |b the future of laboratory medicine? /  |c Giuseppe Lippi, Mario Plebani. 
300 |b Graf. prikazi. 
504 |a Bibliografija: 78 jed. 
504 |a Summary. 
520 |a The current scenario of in vitro and in vivo diagnostics can be summarized using the "silo metaphor", where laboratory medicine, pathology and radiology are three conceptually separated diagnostic disciplines, which will increasingly share many comparable features. The substantial progresses in our understanding of biochemical-biological interplays that characterize many human diseases, coupled with extraordinary technical advances, are now generating important multidisciplinary convergences, leading the way to a new frontier, called integrated diagnostics. This new discipline, which is currently defined as convergence of imaging, pathology and laboratory tests with advanced information technology, has an enormous potential for revolutionizing diagnosis and therapeutic management of human diseases, including those causing the largest number of worldwide deaths (i.e. cardiovascular disease, cancer and infectious diseases). However, some important drawbacks should be overcome, mostly represented by insufficient information technology infrastructures, costs and enormous volume of different information that will be integrated and delivered. To overcome these hurdles, some specific strategies should be defined and implemented, such as planning major integration of exiting information systems or developing innovative ones, combining bioinformatics and imaging informatics, using health technology assessment for assessing cost and benefits, providing interpretative comments in integrated reports, developing and using expert systems and neural networks, overcoming cultural and political boundaries for generating multidisciplinary teams and integrated diagnostic algorithms. 
653 0 |a Laboratorijska medicina  |a Integrirana dijagnostika  |a Patologija  |a Radiologija 
700 1 |a Plebani, Mario  |4 aut 
773 0 |t Biochemia medica (Online)  |x 1846-7482  |g 30 (2020), 1 ; str. 18-30  |w nsk.(HR-ZaNSK)000655372 
981 |b Be2020  |b B03/20 
998 |b dalo2107 
856 4 0 |u https://doi.org/10.11613/BM.2020.010501 
856 4 0 |u https://www.biochemia-medica.com/en/journal/30/1/10.11613/BM.2020.010501  |y Biochemia medica (Online) 
856 4 1 |y Digitalna.nsk.hr 
856 4 0 |u https://hrcak.srce.hr/234032  |y Hrčak