Organocatalytic synthesis of α,α–diaryl substituted α–amino acid derivatives by an interrupted three-component Ugi reaction

An organocatalytic interrupted three-component Ugi reaction for the synthesis of α,α–diaryl α–amino acid derivatives is described. The transformation proceeds with a range of isocyanides and 3-aryl isoindolinone alcohols using Brønsted acid catalysts to afford products in good to excellent yields. B...

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Permalink: http://skupnikatalog.nsk.hr/Record/nsk.NSK01001074265/Details
Matična publikacija: Croatica chemica acta (Online)
92 (2019), 2 ; str. 203-209
Glavni autori: Glavač, Danijel (Author), Jerić, Ivanka, Gredičak, Matija
Vrsta građe: e-članak
Jezik: eng
Predmet:
Online pristup: https://doi.org/10.5562/cca3536
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245 1 0 |a Organocatalytic synthesis of α,α–diaryl substituted α–amino acid derivatives by an interrupted three-component Ugi reaction  |h [Elektronička građa] /  |c Danijel Glavač, Ivanka Jerić, Matija Gredičak. 
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504 |a Summary. 
520 |a An organocatalytic interrupted three-component Ugi reaction for the synthesis of α,α–diaryl α–amino acid derivatives is described. The transformation proceeds with a range of isocyanides and 3-aryl isoindolinone alcohols using Brønsted acid catalysts to afford products in good to excellent yields. Based on the obtained results, a reaction mechanism is proposed and discussed. 
653 0 |a Organokatalitička sinteza  |a Heterociklički spojevi  |a Aminokiseline  |a Indol  |a Derivati  |a Ugi reakcija  |a Biološka aktivnost  |a Antihipertenzivi  |a Antikonvulzivno djelovanje  |a Anksiolitici 
700 1 |a Jerić, Ivanka  |4 aut 
700 1 |a Gredičak, Matija  |4 aut 
773 0 |t Croatica chemica acta (Online)  |x 1334-417X  |g 92 (2019), 2 ; str. 203-209  |w nsk.(HR-ZaNSK)000255036 
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