TiO2 sol-gel coating as a transducer substrate for impedimetric immunosensors

Given the importance of the transducer elements in the performance of sensors for various applications, as well as the growing search for devices that are capable of providing the response in shorter time, in this work, titanium dioxide was examined as a candidate for application in an electrochemic...

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Permalink: http://skupnikatalog.nsk.hr/Record/nsk.NSK01001068869/Details
Matična publikacija: Chemical & biochemical engineering quarterly (Online)
33 (2019), 4 ; str. 437-447
Glavni autori: Dorledo de Faria, Ricardo Adriano (Author), Houmard, Manuel, Martins do Rosário, Verônica Aparecida, Cunha Lins, Vanessa de Freitas, Dias Heneine, Luiz Guilherme, Matencio, Tulio
Vrsta građe: e-članak
Jezik: eng
Predmet:
Online pristup: https://doi.org/10.15255/CABEQ.2019.1699
Chemical & biochemical engineering quarterly (Online)
Hrčak
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080 1 |a 66  |2 2011 
100 1 |a Dorledo de Faria, Ricardo Adriano  |4 aut  |9 HR-ZaNSK 
245 1 0 |a TiO2 sol-gel coating as a transducer substrate for impedimetric immunosensors  |h [Elektronička građa] /  |c Ricardo Adriano Dorledo de Faria, Manuel Houmard, Verônica Aparecida Martins do Rosário, Vanessa de Freitas Cunha Lins, Luiz Guilherme Dias Heneine, Tulio Matencio. 
246 3 |a Titanium dioxide sol-gel 
300 |b Graf. prikazi. 
504 |a Bibliografija: 64 jed. 
504 |a Summary. 
520 |a Given the importance of the transducer elements in the performance of sensors for various applications, as well as the growing search for devices that are capable of providing the response in shorter time, in this work, titanium dioxide was examined as a candidate for application in an electrochemical biosensor. A TiO2 coating deposited by sol-gel method on a silicon wafer was obtained with an anatase crystalline structure, as an n-type semiconductor with donor density equal to 2.954 · 1017 cm–3. Its surface was functionalized to be tested as a biosensor to detect snake venom of the Bothrops genera, and each step of the functionalization was investigated using Electrochemical Impedance Spectroscopy (EIS) and Cyclic voltammetry. Despite being less sensitive than the reference method ELISA, the TiO2-based biosensor was also capable of detecting the analyte of interest at 20 μg mL–1, revealing an increase in its leakage resistance and phase shift after incubation in this solution. Furthermore, the total time for carrying out the biodetection with the TiO2-coated device (41.24 ± 0.05 min) was estimated to be approximately 80 % shorter than that required by the labelled standard assay, which indicates that TiO2 is a promising electrochemical transducer for biosensing applications. 
653 0 |a Titanijev dioksid  |a Pretvarači  |a Biosenzori  |a Imunosenzori  |a Sol-gel postupak  |a Poluvodiči  |a Elektrokemijska impedancijska spektroskopija  |a Ciklička voltametrija 
700 1 |a Houmard, Manuel  |4 aut  |9 HR-ZaNSK 
700 1 |a Martins do Rosário, Verônica Aparecida  |4 aut  |9 HR-ZaNSK 
700 1 |a Cunha Lins, Vanessa de Freitas  |4 aut  |9 HR-ZaNSK 
700 1 |a Dias Heneine, Luiz Guilherme  |4 aut  |9 HR-ZaNSK 
700 1 |a Matencio, Tulio  |4 aut  |9 HR-ZaNSK 
773 0 |t Chemical & biochemical engineering quarterly (Online)  |x 1846-5153  |g 33 (2019), 4 ; str. 437-447  |w nsk.(HR-ZaNSK)000622963 
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856 4 0 |u https://doi.org/10.15255/CABEQ.2019.1699 
856 4 0 |u http://silverstripe.fkit.hr/cabeq/past-issues/article/1699  |y Chemical & biochemical engineering quarterly (Online) 
856 4 0 |u https://hrcak.srce.hr/232512  |y Hrčak 
856 4 1 |y Digitalna.nsk.hr