Effects of iron supplementation on iron nutrition status and cognitive functions in children
This study examined the effect of iron supplementation on cognitive function by a double-blind intervention trial in nine-year-old mildly anaemic schoolchildren. Their nutritional status was assessed by anthropometric measurements and the following biochemical values: haemoglobin, haematocrit, red b...
Permalink: | http://skupnikatalog.nsk.hr/Record/ffzg.KOHA-OAI-FFZG:306554/Details |
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Matična publikacija: |
Food and Nutrition Bulletin 19 (1998), 4 ; str. 298-306 |
Glavni autori: | Buzina-Subotičanec, Kornelija (-), Buzina, Ratko (Author), Stavljenić, Ana Tadinac-Babić, Meri, Juhović-Markus, Vesna |
Vrsta građe: | Članak |
Jezik: | eng |
LEADER | 03176naa a2200277uu 4500 | ||
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008 | 131105s1998 xx eng|d | ||
022 | |a 0379-5721 | ||
035 | |a (CROSBI)239513 | ||
040 | |a HR-ZaFF |b hrv |c HR-ZaFF |e ppiak | ||
100 | 1 | |a Buzina-Subotičanec, Kornelija | |
245 | 1 | 0 | |a Effects of iron supplementation on iron nutrition status and cognitive functions in children / |c Buzina-Subotičanec, Kornelija ; Buzina, Ratko ; Stavljenić, Ana ; Tadinac-Babić, Meri ; Juhović-Markus, Vesna. |
246 | 3 | |i Naslov na engleskom: |a Effects of iron supplementation on iron nutrition status and cognitive functions in children | |
300 | |a 298-306 |f str. | ||
363 | |a 19 |b 4 |i 1998 | ||
520 | |a This study examined the effect of iron supplementation on cognitive function by a double-blind intervention trial in nine-year-old mildly anaemic schoolchildren. Their nutritional status was assessed by anthropometric measurements and the following biochemical values: haemoglobin, haematocrit, red blood cell count (RBC), mean corpuscular haemoglobin (MCH), mean corpuscular volume (MCV), mean corpuscular haemoglobin concentration (MCHC), serum iron, total iron-binding capacity (TIBC), and transferrin saturation. The cognitive assessment was performed using an abbreviated Wechsler Intelligence Scale for Children-Revised (WISC-R) containing six subtests in order to obtain information on both verbal and non-verbal aspects of intelligence. There were highly significant correlations of the WISC-R scores with initial height-for-age, haemoglobin, haematocrit, and transferrin saturation, and a correlation with MCHC. After completion of the baseline examination, one group of children was given a supplement containing 100 mg of iron for 10 weeks while the other group received a placebo. Iron supplementation had a positive effect on the biochemical measures of iron status and statistically significant improvement in total WISC-R score (p<.01). This effect was primarily the result of improved performance on nonverbal subtests, of which improvements in block design and coding were statistically significant (p<.01). The small increase in the sum of scaled scores from the verbal subtest was not significant (p>.05), but within the verbal subtest there was a significant improvement on the similarities part of the test (p<.05). The effects of iron supplementation were more pronounced in children with initially lower haemoglobin values. It is concluded that iron supplementation in nine-year-old schoolchildren with haemoglobin levels between 110 and 119 g/L will result in an improvement of cognitive functions, even though they are not otherwise malnourished. | ||
546 | |a ENG | ||
690 | |a 3.03 | ||
690 | |a 5.06 | ||
693 | |a iron supplementation, nutrition status, cognitive functions |l hrv |2 crosbi | ||
693 | |a iron supplementation, nutrition status, cognitive functions |l eng |2 crosbi | ||
700 | 1 | |a Buzina, Ratko |4 aut | |
700 | 1 | |a Stavljenić, Ana |4 aut |a Tadinac-Babić, Meri | |
700 | 1 | |a Juhović-Markus, Vesna |4 aut | |
773 | 0 | |t Food and Nutrition Bulletin |x 0379-5721 |g 19 (1998), 4 ; str. 298-306 | |
942 | |c CLA |t 1.01 |u 1 |z Znanstveni - clanak | ||
999 | |c 306554 |d 306552 |