Effects of (desgly - arg) vasopressin on cognitive processes in alcoholic patients

The effect of intranasally administered (DesGly9-Arg8) vasopressin (DGAVP) on certain aspects of cognitive functions of alcoholic patients was studied. The investigation was carried out in 103 chronic alcoholic patients. None of the patients suffered from Korsakoff's syndrome, portal encephalop...

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Permalink: http://skupnikatalog.nsk.hr/Record/ffzg.KOHA-OAI-FFZG:306547/Details
Matična publikacija: Acta medica Iugoslavica
45 (1991), str. 223-230
Glavni autori: Koršić, Mirko (-), Jokić, Nataša (Author), Ilić-Supek, D. Skočilić, Ž, Lovrić, Martina Bačić, Jasna, Jakovljević, Miro Maslo, Ksenija, Trbović, Marko
Vrsta građe: Članak
Jezik: eng
LEADER 02253naa a2200277uu 4500
008 131105s1991 xx eng|d
022 |a 0375-8338 
035 |a (CROSBI)238651 
040 |a HR-ZaFF  |b hrv  |c HR-ZaFF  |e ppiak 
100 1 |a Koršić, Mirko 
245 1 0 |a Effects of (desgly - arg) vasopressin on cognitive processes in alcoholic patients /  |c Koršić, Mirko ; Jokić, Nataša ; Ilić-Supek, D. ; Skočilić, Ž. ; Lovrić, Martina ; Bačić, Jasna ; Jakovljević, Miro ; Maslo, Ksenija ; Trbović, Marko. 
246 3 |i Naslov na engleskom:  |a Effects of (desgly - arg) vasopressin on cognitive processes in alcoholic patients 
300 |a 223-230  |f str. 
363 |a 45  |i 1991 
520 |a The effect of intranasally administered (DesGly9-Arg8) vasopressin (DGAVP) on certain aspects of cognitive functions of alcoholic patients was studied. The investigation was carried out in 103 chronic alcoholic patients. None of the patients suffered from Korsakoff's syndrome, portal encephalopathy or brain damage of other etiology. The trial was double-blind, placebo controlled. Psychological testing, which included certain aspects of attention, short-term and long-term memory and spatial orientation, was carried out on the day before (baseline measurements), on the last day (II), and seven days after the last administration of DGAVP (III). No treatment effect of DGAVP was observed. The results show that investigations with humans are infinitely more complex than those with animals, since a number of physiological and socio-psychological factors must be controlled. In this study of alcoholics two such factors: 1) duration of abstinence and 2) adaptation to test situation were identified. 
546 |a ENG 
693 |a vasopressin, cognitive processes, alcoholic patients  |l hrv  |2 crosbi 
693 |a vasopressin, cognitive processes, alcoholic patients  |l eng  |2 crosbi 
700 1 |a Jokić, Nataša  |4 aut 
700 1 |a Ilić-Supek, D.  |4 aut  |a Skočilić, Ž. 
700 1 |a Lovrić, Martina  |4 aut  |a Bačić, Jasna 
700 1 |a Jakovljević, Miro  |4 aut  |a Maslo, Ksenija 
700 1 |a Trbović, Marko  |4 aut 
773 0 |t Acta medica Iugoslavica  |x 0375-8338  |g 45 (1991), str. 223-230 
942 |c CLA  |t 1.01  |u 1  |z Znanstveni - clanak 
999 |c 306547  |d 306545